2022 Atlantic Coast Conference Leaders First Downs - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Florida State | 11 | 125 | 117 | 23 | 265 | 24.1 |
| 1 | Pittsburgh | 11 | 125 | 95 | 11 | 231 | 21.0 |
| 3 | Duke | 12 | 121 | 117 | 26 | 264 | 22.0 |
| 4 | Clemson | 10 | 105 | 103 | 22 | 230 | 23.0 |
| 5 | Louisville | 10 | 94 | 97 | 19 | 210 | 21.0 |
| 6 | North Carolina | 10 | 93 | 145 | 17 | 255 | 25.5 |
| 7 | Wake Forest | 11 | 88 | 163 | 23 | 274 | 24.9 |
| 8 | North Carolina State | 11 | 85 | 116 | 25 | 226 | 20.5 |
| 9 | Miami (Florida) | 9 | 84 | 113 | 20 | 217 | 24.1 |
| 10 | Syracuse | 9 | 83 | 115 | 15 | 213 | 23.7 |
| 11 | Virginia | 9 | 69 | 85 | 23 | 177 | 19.7 |
| 12 | Virginia Tech | 10 | 64 | 89 | 18 | 171 | 17.1 |
| 13 | Georgia Tech | 8 | 62 | 74 | 15 | 151 | 18.9 |
| 14 | Boston College | 9 | 51 | 98 | 13 | 162 | 18.0 |