2022 Atlantic Coast Conference Leaders Sacks - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Pittsburgh | 11 | 42.0 | 299 | 3.82 |
| 1 | Louisville | 10 | 42.0 | 297 | 4.20 |
| 3 | Duke | 12 | 35.0 | 240 | 2.92 |
| 4 | Clemson | 10 | 33.0 | 220 | 3.30 |
| 4 | Florida State | 11 | 33.0 | 218 | 3.00 |
| 6 | Miami (Florida) | 9 | 31.0 | 141 | 3.44 |
| 7 | Virginia | 9 | 30.0 | 167 | 3.33 |
| 8 | Wake Forest | 11 | 28.0 | 218 | 2.55 |
| 9 | North Carolina State | 11 | 27.0 | 192 | 2.46 |
| 10 | Syracuse | 9 | 25.0 | 146 | 2.78 |
| 10 | Boston College | 9 | 25.0 | 139 | 2.78 |
| 12 | Virginia Tech | 10 | 22.0 | 153 | 2.20 |
| 12 | Georgia Tech | 8 | 22.0 | 127 | 2.75 |
| 14 | North Carolina | 10 | 14.0 | 102 | 1.40 |