2022 American Athletic Conference Leaders Rushing Defense - Games in October Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulane | 3 | 84 | 352 | 4.19 | 2 | 28.00 | 117.33 |
| 2 | Navy | 5 | 140 | 530 | 3.79 | 3 | 28.00 | 106.00 |
| 3 | Houston | 3 | 122 | 511 | 4.19 | 5 | 40.67 | 170.33 |
| 4 | UCF | 4 | 109 | 354 | 3.25 | 6 | 27.25 | 88.50 |
| 5 | East Carolina | 5 | 177 | 701 | 3.96 | 7 | 35.40 | 140.20 |
| 6 | Memphis | 4 | 128 | 504 | 3.94 | 8 | 32.00 | 126.00 |
| 7 | Cincinnati | 4 | 171 | 598 | 3.50 | 9 | 42.75 | 149.50 |
| 7 | South Florida | 4 | 143 | 669 | 4.68 | 9 | 35.75 | 167.25 |
| 7 | Tulsa | 4 | 177 | 895 | 5.06 | 9 | 44.25 | 223.75 |
| 10 | SMU | 4 | 196 | 893 | 4.56 | 10 | 49.00 | 223.25 |
| 11 | Temple | 4 | 201 | 963 | 4.79 | 12 | 50.25 | 240.75 |