2022 American Athletic Conference Leaders Scoring Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 9 | 22 | 8 | 19 | 0 | 2 | 179 | 19.9 |
| 2 | Tulane | 11 | 32 | 11 | 31 | 0 | 0 | 256 | 23.3 |
| 3 | Navy | 11 | 32 | 18 | 30 | 1 | 0 | 278 | 25.3 |
| 4 | UCF | 10 | 32 | 12 | 27 | 3 | 0 | 261 | 26.1 |
| 5 | Memphis | 11 | 37 | 10 | 31 | 3 | 0 | 289 | 26.3 |
| 6 | East Carolina | 11 | 40 | 13 | 37 | 3 | 0 | 322 | 29.3 |
| 7 | Houston | 11 | 42 | 16 | 35 | 1 | 0 | 337 | 30.6 |
| 8 | Temple | 9 | 38 | 8 | 37 | 1 | 0 | 291 | 32.3 |
| 9 | Tulsa | 10 | 40 | 21 | 38 | 1 | 1 | 345 | 34.5 |
| 10 | SMU | 10 | 45 | 11 | 39 | 2 | 1 | 348 | 34.8 |
| 11 | South Florida | 9 | 52 | 12 | 50 | 1 | 1 | 402 | 44.7 |