2022 American Athletic Conference Leaders Scoring Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 1 | 3 | 1 | 3 | 0 | 0 | 24 | 24.0 |
| 2 | Cincinnati | 1 | 3 | 2 | 3 | 0 | 0 | 27 | 27.0 |
| 2 | Tulsa | 1 | 3 | 2 | 3 | 0 | 0 | 27 | 27.0 |
| 2 | Houston | 1 | 4 | 0 | 3 | 0 | 0 | 27 | 27.0 |
| 5 | Tulane | 2 | 7 | 2 | 7 | 0 | 0 | 55 | 27.5 |
| 6 | Navy | 1 | 5 | 0 | 5 | 0 | 0 | 35 | 35.0 |
| 7 | UCF | 2 | 10 | 2 | 10 | 0 | 0 | 76 | 38.0 |
| 8 | Memphis | 2 | 12 | 1 | 12 | 0 | 0 | 87 | 43.5 |
| 9 | South Florida | 1 | 6 | 1 | 6 | 0 | 0 | 45 | 45.0 |
| 10 | SMU | 2 | 14 | 1 | 14 | 0 | 0 | 101 | 50.5 |