2022 Mid-American Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Toledo | 5 | 850 | 814 | 307 | 1664 | 5.42 | 332.8 |
| 2 | Miami (Ohio) | 5 | 472 | 1332 | 327 | 1804 | 5.52 | 360.8 |
| 3 | Western Michigan | 4 | 607 | 842 | 245 | 1449 | 5.91 | 362.3 |
| 4 | Ball State | 4 | 663 | 858 | 281 | 1521 | 5.41 | 380.3 |
| 5 | Central Michigan | 4 | 477 | 1132 | 298 | 1609 | 5.40 | 402.3 |
| 6 | Eastern Michigan | 5 | 760 | 1296 | 339 | 2056 | 6.06 | 411.2 |
| 7 | Buffalo | 5 | 790 | 1281 | 308 | 2071 | 6.72 | 414.2 |
| 8 | Northern Illinois | 4 | 548 | 1156 | 262 | 1704 | 6.50 | 426.0 |
| 9 | Kent State | 4 | 635 | 1156 | 283 | 1791 | 6.33 | 447.8 |
| 10 | Akron | 4 | 844 | 1090 | 290 | 1934 | 6.67 | 483.5 |
| 11 | Ohio | 5 | 753 | 1691 | 352 | 2444 | 6.94 | 488.8 |
| 12 | Bowling Green | 5 | 863 | 1624 | 386 | 2487 | 6.44 | 497.4 |