2023 Conference USA Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/08/2024
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | New Mexico State | 1 | 65 | 148 | 45 | 213 | 4.73 | 213.0 |
| 2 | Western Kentucky | 1 | 204 | 358 | 60 | 562 | 9.37 | 562.0 |
| 3 | Louisiana Tech | 1 | 312 | 107 | 66 | 419 | 6.35 | 419.0 |
| 4 | Liberty | 1 | 183 | 401 | 71 | 584 | 8.23 | 584.0 |
| 5 | Jacksonville State | 1 | 89 | 399 | 77 | 488 | 6.34 | 488.0 |
| 6 | Florida International | 1 | 323 | 187 | 83 | 510 | 6.14 | 510.0 |
| 7 | UTEP | 2 | 428 | 507 | 123 | 935 | 7.60 | 467.5 |
| 8 | Middle Tennessee | 2 | 317 | 430 | 129 | 747 | 5.79 | 373.5 |
| 9 | Sam Houston State | 2 | 298 | 497 | 146 | 795 | 5.45 | 397.5 |