2015 Conference USA Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/11/2016
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida Atlantic | 2 | 356 | 422 | 139 | 778 | 5.60 | 389.0 |
| 2 | Louisiana Tech | 2 | 258 | 542 | 144 | 800 | 5.56 | 400.0 |
| 3 | Old Dominion | 1 | 256 | 179 | 79 | 435 | 5.51 | 435.0 |
| 4 | Florida International | 1 | 205 | 234 | 85 | 439 | 5.16 | 439.0 |
| 5 | Middle Tennessee | 3 | 597 | 727 | 242 | 1324 | 5.47 | 441.3 |
| 6 | UTSA | 3 | 560 | 784 | 207 | 1344 | 6.49 | 448.0 |
| 7 | North Texas | 2 | 447 | 450 | 141 | 897 | 6.36 | 448.5 |
| 8 | Marshall | 1 | 184 | 270 | 95 | 454 | 4.78 | 454.0 |
| 9 | Western Kentucky | 3 | 663 | 858 | 225 | 1521 | 6.76 | 507.0 |
| 10 | Rice | 2 | 576 | 494 | 116 | 1070 | 9.22 | 535.0 |
| 11 | Charlotte | 1 | 415 | 129 | 73 | 544 | 7.45 | 544.0 |
| 11 | Southern Mississippi | 3 | 743 | 889 | 218 | 1632 | 7.49 | 544.0 |
| 13 | UTEP | 2 | 411 | 753 | 126 | 1164 | 9.24 | 582.0 |