2020 Conference USA Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Charlotte | 1 | 274 | 127 | 51 | 401 | 7.86 | 401.0 |
| 2 | Western Kentucky | 1 | 144 | 343 | 72 | 487 | 6.76 | 487.0 |
| 3 | Louisiana Tech | 1 | 333 | 161 | 49 | 494 | 10.08 | 494.0 |
| 4 | UAB | 1 | 337 | 158 | 79 | 495 | 6.27 | 495.0 |
| 5 | UTEP | 1 | 208 | 481 | 74 | 689 | 9.31 | 689.0 |