2016 Atlantic Coast Conference Leaders Total Defense - Games in November Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida State | 4 | 356 | 699 | 266 | 1055 | 3.97 | 263.8 |
| 2 | Clemson | 4 | 443 | 713 | 251 | 1156 | 4.61 | 289.0 |
| 3 | Boston College | 4 | 534 | 805 | 250 | 1339 | 5.36 | 334.8 |
| 4 | Louisville | 4 | 423 | 941 | 286 | 1364 | 4.77 | 341.0 |
| 5 | Wake Forest | 4 | 798 | 611 | 272 | 1409 | 5.18 | 352.3 |
| 6 | Virginia Tech | 4 | 844 | 570 | 278 | 1414 | 5.09 | 353.5 |
| 7 | Miami (Florida) | 4 | 410 | 1020 | 286 | 1430 | 5.00 | 357.5 |
| 8 | North Carolina State | 4 | 353 | 1086 | 251 | 1439 | 5.73 | 359.8 |
| 9 | Virginia | 4 | 936 | 723 | 254 | 1659 | 6.53 | 414.8 |
| 10 | Duke | 4 | 709 | 1122 | 262 | 1831 | 6.99 | 457.8 |
| 11 | North Carolina | 4 | 1204 | 644 | 314 | 1848 | 5.89 | 462.0 |
| 12 | Georgia Tech | 4 | 856 | 1028 | 308 | 1884 | 6.12 | 471.0 |
| 13 | Pittsburgh | 4 | 481 | 1619 | 352 | 2100 | 5.97 | 525.0 |
| 14 | Syracuse | 4 | 1106 | 1301 | 301 | 2407 | 8.00 | 601.8 |