2018 Conference USA Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 9 | 933 | 1589 | 544 | 2522 | 4.64 | 280.2 |
| 2 | Charlotte | 10 | 1257 | 2312 | 590 | 3569 | 6.05 | 356.9 |
| 3 | UTSA | 9 | 1402 | 2378 | 620 | 3780 | 6.10 | 420.0 |
| 4 | Rice | 10 | 1667 | 2782 | 655 | 4449 | 6.79 | 444.9 |
| 5 | Florida International | 10 | 1866 | 1921 | 662 | 3787 | 5.72 | 378.7 |
| 6 | Western Kentucky | 9 | 1494 | 2458 | 663 | 3952 | 5.96 | 439.1 |
| 7 | UTEP | 10 | 1897 | 2009 | 666 | 3906 | 5.86 | 390.6 |
| 8 | Louisiana Tech | 10 | 1369 | 1841 | 674 | 3210 | 4.76 | 321.0 |
| 9 | Middle Tennessee | 10 | 1563 | 2113 | 706 | 3676 | 5.21 | 367.6 |
| 10 | Marshall | 10 | 949 | 2311 | 709 | 3260 | 4.60 | 326.0 |
| 11 | Florida Atlantic | 10 | 1797 | 2314 | 743 | 4111 | 5.53 | 411.1 |
| 12 | Old Dominion | 10 | 2207 | 2562 | 755 | 4769 | 6.32 | 476.9 |
| 13 | UAB | 12 | 1246 | 2321 | 766 | 3567 | 4.66 | 297.3 |
| 14 | North Texas | 11 | 1288 | 2950 | 778 | 4238 | 5.45 | 385.3 |