2021 Conference USA Leaders Opponent Penalties - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 7 | 55 | 493 | 7.9 | 70.4 |
| 2 | Western Kentucky | 8 | 53 | 452 | 6.6 | 56.5 |
| 3 | Old Dominion | 7 | 51 | 464 | 7.3 | 66.3 |
| 3 | Middle Tennessee | 8 | 51 | 425 | 6.4 | 53.1 |
| 5 | North Texas | 7 | 50 | 425 | 7.1 | 60.7 |
| 6 | UTEP | 7 | 49 | 485 | 7.0 | 69.3 |
| 7 | Louisiana Tech | 6 | 47 | 452 | 7.8 | 75.3 |
| 8 | Marshall | 7 | 46 | 411 | 6.6 | 58.7 |
| 9 | Florida Atlantic | 6 | 45 | 402 | 7.5 | 67.0 |
| 9 | UAB | 8 | 45 | 368 | 5.6 | 46.0 |
| 11 | Charlotte | 6 | 44 | 384 | 7.3 | 64.0 |
| 12 | Rice | 6 | 40 | 367 | 6.7 | 61.2 |
| 13 | Southern Mississippi | 6 | 39 | 352 | 6.5 | 58.7 |
| 14 | Florida International | 6 | 28 | 276 | 4.7 | 46.0 |