2021 Big 12 Conference Leaders All Purpose - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | D'Shawn Jamison | Texas | SR | DB | 6 | 0 | 0 | 85 | 199 | 18 | 284 | 15.8 | 47.3 |
| 2 | Adrian Frye | Texas Tech | SR | DB | 5 | 0 | 0 | 69 | 0 | 9 | 69 | 7.7 | 13.8 |
| 3 | Brennan Presley | Okla St | SO | WR | 7 | 14 | 273 | 65 | 272 | 41 | 624 | 15.2 | 89.1 |
| 4 | Trestan Ebner | Baylor | SR | RB | 7 | 449 | 236 | 56 | 313 | 113 | 1054 | 9.3 | 150.6 |
| 5 | Isaiah Esdale | WVU | SR | WR | 5 | -7 | 261 | 50 | 0 | 29 | 304 | 10.5 | 60.8 |
| 6 | Xavier Worthy | Texas | FR | WR | 6 | 0 | 450 | 47 | 0 | 40 | 497 | 12.4 | 82.8 |
| 6 | Kwamie Lassiter II | Kansas | SR | WR | 6 | 0 | 265 | 47 | 0 | 29 | 312 | 10.8 | 52.0 |
| 8 | Derius Davis | TCU | SR | WR | 7 | 38 | 322 | 43 | 111 | 37 | 514 | 13.9 | 73.4 |
| 9 | Myles Price | Texas Tech | SO | WR | 6 | 12 | 312 | 37 | 0 | 27 | 361 | 13.4 | 60.2 |
| 10 | Keilan Robinson | Texas | JR | RB | 5 | 184 | 27 | 28 | 0 | 30 | 239 | 8.0 | 47.8 |
| 11 | Marvin Mims | Oklahoma | SO | WR | 7 | 0 | 406 | 25 | 51 | 26 | 482 | 18.5 | 68.9 |
| 12 | Jaylin Noel | Iowa State | FR | WR | 6 | 0 | 47 | 18 | 131 | 22 | 196 | 8.9 | 32.7 |
| 13 | Phillip Brooks | Kansas St | JR | WR | 7 | 3 | 297 | 12 | 31 | 31 | 343 | 11.1 | 49.0 |
| 14 | Tarique Milton | Iowa State | SR | WR | 6 | 0 | 193 | 11 | 0 | 12 | 204 | 17.0 | 34.0 |
| 15 | Ty Bowman | Kansas St | FR | WR | 4 | 0 | 0 | 9 | 0 | 1 | 9 | 9.0 | 2.3 |
| 16 | Darien Porter | Iowa State | SO | WR | 6 | 0 | 0 | 8 | 0 | 1 | 8 | 8.0 | 1.3 |
| 17 | Graeson Malashevich | WVU | SO | WR | 6 | 0 | 0 | 7 | 38 | 6 | 45 | 7.5 | 7.5 |
| 18 | Marcus Washington | Texas | JR | WR | 6 | 0 | 197 | 5 | 0 | 11 | 202 | 18.4 | 33.7 |
| 19 | Jaden Nixon | Okla St | FR | RB | 2 | 122 | 3 | 2 | 15 | 17 | 142 | 8.4 | 71.0 |