2021 Big 12 Conference Leaders All Purpose - Games in August/September Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Trestan Ebner | Baylor | SR | RB | 4 | 348 | 77 | 87 | 152 | 68 | 664 | 9.8 | 166.0 |
| 2 | Brennan Presley | Okla St | SO | WR | 4 | -4 | 162 | 61 | 99 | 23 | 318 | 13.8 | 79.5 |
| 3 | D'Shawn Jamison | Texas | SR | DB | 4 | 0 | 0 | 54 | 76 | 8 | 130 | 16.3 | 32.5 |
| 4 | Xavier Worthy | Texas | FR | WR | 4 | 0 | 246 | 47 | 0 | 17 | 293 | 17.2 | 73.3 |
| 5 | Derius Davis | TCU | SR | WR | 3 | 0 | 103 | 31 | 0 | 10 | 134 | 13.4 | 44.7 |
| 6 | Jaylin Noel | Iowa State | FR | WR | 4 | 0 | 27 | 30 | 0 | 12 | 57 | 4.8 | 14.3 |
| 7 | Keilan Robinson | Texas | JR | RB | 4 | 175 | 0 | 28 | 0 | 24 | 203 | 8.5 | 50.8 |
| 8 | Adrian Frye | Texas Tech | SR | DB | 4 | 0 | 0 | 27 | 0 | 6 | 27 | 4.5 | 6.8 |
| 9 | Marvin Mims | Oklahoma | SO | WR | 4 | 0 | 193 | 25 | 31 | 17 | 249 | 14.6 | 62.3 |
| 9 | Kwamie Lassiter II | Kansas | SR | WR | 4 | 0 | 210 | 25 | 0 | 18 | 235 | 13.1 | 58.8 |
| 11 | Isaiah Esdale | WVU | SR | WR | 4 | -7 | 110 | 17 | 0 | 15 | 120 | 8.0 | 30.0 |
| 12 | Tarique Milton | Iowa State | SR | WR | 4 | 0 | 59 | 11 | 0 | 8 | 70 | 8.8 | 17.5 |
| 13 | Myles Price | Texas Tech | SO | WR | 4 | 12 | 108 | 10 | 0 | 15 | 130 | 8.7 | 32.5 |
| 13 | Graeson Malashevich | WVU | SO | WR | 4 | 0 | 0 | 10 | 0 | 2 | 10 | 5.0 | 2.5 |
| 15 | McLane Mannix | Texas Tech | SR | WR | 3 | 0 | 2 | 8 | 0 | 4 | 10 | 2.5 | 3.3 |
| 16 | Phillip Brooks | Kansas St | JR | WR | 4 | 3 | 170 | 3 | 31 | 16 | 207 | 12.9 | 51.8 |