2021 Big 12 Conference Leaders All Purpose - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Trestan Ebner | Baylor | SR | RB | 9 | 610 | 222 | 125 | 348 | 151 | 1305 | 8.6 | 145.0 |
| 2 | Kwamie Lassiter II | Kansas | SR | WR | 9 | 0 | 528 | 108 | 0 | 56 | 636 | 11.4 | 70.7 |
| 3 | Phillip Brooks | Kansas St | JR | WR | 10 | -7 | 415 | 88 | 62 | 43 | 558 | 13.0 | 55.8 |
| 4 | D'Shawn Jamison | Texas | SR | DB | 7 | 0 | 0 | 79 | 272 | 20 | 366 | 18.3 | 52.3 |
| 5 | Adrian Frye | Texas Tech | SR | DB | 7 | 0 | 0 | 69 | 0 | 9 | 69 | 7.7 | 9.9 |
| 6 | Brennan Presley | Okla St | SO | WR | 10 | 27 | 396 | 68 | 224 | 59 | 715 | 12.1 | 71.5 |
| 7 | Derius Davis | TCU | SR | WR | 9 | 34 | 424 | 63 | 278 | 50 | 799 | 16.0 | 88.8 |
| 8 | Isaiah Esdale | WVU | SR | WR | 8 | -7 | 313 | 49 | 0 | 36 | 355 | 9.9 | 44.4 |
| 9 | Marvin Mims | Oklahoma | SO | WR | 10 | 0 | 627 | 41 | 51 | 37 | 719 | 19.4 | 71.9 |
| 9 | Jaylin Noel | Iowa State | FR | WR | 8 | 0 | 148 | 41 | 208 | 37 | 397 | 10.7 | 49.6 |
| 11 | Myles Price | Texas Tech | SO | WR | 9 | 75 | 485 | 37 | 0 | 44 | 597 | 13.6 | 66.3 |
| 12 | Xavier Worthy | Texas | FR | WR | 7 | 0 | 502 | 29 | 15 | 44 | 546 | 12.4 | 78.0 |
| 13 | Keilan Robinson | Texas | JR | RB | 6 | 271 | 33 | 28 | 0 | 36 | 332 | 9.2 | 55.3 |
| 14 | Graeson Malashevich | WVU | SO | WR | 10 | 0 | 0 | 10 | 20 | 4 | 30 | 7.5 | 3.0 |
| 15 | Ty Bowman | Kansas St | FR | WR | 7 | 0 | 0 | 9 | 0 | 1 | 9 | 9.0 | 1.3 |
| 16 | Darien Porter | Iowa State | SO | WR | 8 | 0 | 0 | 8 | 0 | 1 | 8 | 8.0 | 1.0 |
| 17 | Marcus Washington | Texas | JR | WR | 7 | 0 | 147 | 5 | 0 | 10 | 152 | 15.2 | 21.7 |
| 17 | McLane Mannix | Texas Tech | SR | WR | 7 | 16 | 28 | 5 | 0 | 7 | 49 | 7.0 | 7.0 |
| 19 | Jaden Nixon | Okla St | FR | RB | 2 | 122 | 3 | 2 | 15 | 17 | 142 | 8.4 | 71.0 |