2021 Big 12 Conference Leaders Penalties - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Texas | 3 | 13 | 96 | 4.3 | 32.0 |
| 2 | Baylor | 4 | 19 | 186 | 4.8 | 46.5 |
| 3 | Iowa State | 4 | 23 | 178 | 5.8 | 44.5 |
| 3 | West Virginia | 4 | 23 | 180 | 5.8 | 45.0 |
| 5 | Kansas | 3 | 18 | 159 | 6.0 | 53.0 |
| 6 | Oklahoma State | 4 | 26 | 223 | 6.5 | 55.8 |
| 7 | TCU | 3 | 20 | 165 | 6.7 | 55.0 |
| 8 | Kansas State | 4 | 27 | 238 | 6.8 | 59.5 |
| 8 | Texas Tech | 4 | 27 | 242 | 6.8 | 60.5 |
| 10 | Oklahoma | 4 | 28 | 256 | 7.0 | 64.0 |