2021 Big 12 Conference Leaders Penalties - Games in October Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Texas Tech | 5 | 18 | 140 | 3.6 | 28.0 |
| 2 | Baylor | 4 | 16 | 127 | 4.0 | 31.8 |
| 2 | Kansas | 4 | 16 | 140 | 4.0 | 35.0 |
| 4 | Iowa State | 4 | 18 | 144 | 4.5 | 36.0 |
| 5 | Oklahoma State | 4 | 21 | 202 | 5.3 | 50.5 |
| 6 | Oklahoma | 5 | 30 | 240 | 6.0 | 48.0 |
| 6 | West Virginia | 4 | 24 | 216 | 6.0 | 54.0 |
| 8 | TCU | 5 | 33 | 321 | 6.6 | 64.2 |
| 9 | Kansas State | 4 | 27 | 204 | 6.8 | 51.0 |
| 10 | Texas | 4 | 28 | 235 | 7.0 | 58.8 |