2021 Atlantic Coast Conference Leaders Passing Defense - Games Lost Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Boston College | 6 | 149 | 83 | 55.7 | 1117 | 7.5 | 9 | 3 | 134.58 | 24.8 | 186.2 |
| 2 | Clemson | 3 | 114 | 79 | 69.3 | 675 | 5.9 | 6 | 1 | 134.66 | 38.0 | 225.0 |
| 3 | North Carolina State | 3 | 129 | 78 | 60.5 | 909 | 7.0 | 9 | 3 | 138.03 | 43.0 | 303.0 |
| 4 | Virginia Tech | 7 | 195 | 115 | 59.0 | 1597 | 8.2 | 13 | 4 | 145.67 | 27.9 | 228.1 |
| 5 | Florida State | 7 | 238 | 151 | 63.4 | 1852 | 7.8 | 17 | 7 | 146.51 | 34.0 | 264.6 |
| 6 | Miami (Florida) | 5 | 166 | 106 | 63.9 | 1311 | 7.9 | 11 | 2 | 149.66 | 33.2 | 262.2 |
| 7 | Wake Forest | 3 | 80 | 49 | 61.3 | 699 | 8.7 | 5 | 1 | 152.78 | 26.7 | 233.0 |
| 8 | Syracuse | 7 | 212 | 145 | 68.4 | 1535 | 7.2 | 17 | 3 | 152.85 | 30.3 | 219.3 |
| 9 | Pittsburgh | 3 | 129 | 87 | 67.4 | 1137 | 8.8 | 9 | 2 | 161.40 | 43.0 | 379.0 |
| 10 | Louisville | 7 | 228 | 151 | 66.2 | 2117 | 9.3 | 14 | 3 | 161.85 | 32.6 | 302.4 |
| 11 | North Carolina | 7 | 168 | 110 | 65.5 | 1512 | 9.0 | 16 | 2 | 170.13 | 24.0 | 216.0 |
| 12 | Duke | 9 | 313 | 191 | 61.0 | 3102 | 9.9 | 28 | 3 | 171.87 | 34.8 | 344.7 |
| 13 | Virginia | 6 | 168 | 104 | 61.9 | 1584 | 9.4 | 20 | 4 | 175.64 | 28.0 | 264.0 |
| 14 | Georgia Tech | 9 | 247 | 164 | 66.4 | 2567 | 10.4 | 23 | 0 | 184.43 | 27.4 | 285.2 |