2021 Atlantic Coast Conference Leaders Passing Defense - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 11 | 392 | 207 | 52.8 | 2387 | 6.1 | 18 | 14 | 111.97 | 35.6 | 217.0 |
| 2 | Clemson | 12 | 427 | 249 | 58.3 | 2587 | 6.1 | 11 | 11 | 112.56 | 35.6 | 215.6 |
| 3 | Boston College | 11 | 290 | 169 | 58.3 | 1998 | 6.9 | 14 | 8 | 126.57 | 26.4 | 181.6 |
| 4 | Wake Forest | 13 | 394 | 230 | 58.4 | 2854 | 7.2 | 22 | 14 | 130.55 | 30.3 | 219.5 |
| 5 | Florida State | 11 | 359 | 214 | 59.6 | 2556 | 7.1 | 23 | 14 | 132.76 | 32.6 | 232.4 |
| 6 | Pittsburgh | 13 | 482 | 292 | 60.6 | 3640 | 7.6 | 25 | 15 | 134.92 | 37.1 | 280.0 |
| 7 | Virginia Tech | 12 | 369 | 217 | 58.8 | 2837 | 7.7 | 20 | 10 | 135.86 | 30.8 | 236.4 |
| 8 | Miami (Florida) | 11 | 399 | 251 | 62.9 | 2838 | 7.1 | 21 | 7 | 136.52 | 36.3 | 258.0 |
| 9 | Louisville | 12 | 397 | 258 | 65.0 | 3031 | 7.6 | 20 | 8 | 141.72 | 33.1 | 252.6 |
| 10 | Virginia | 11 | 360 | 215 | 59.7 | 2793 | 7.8 | 26 | 8 | 144.28 | 32.7 | 253.9 |
| 11 | North Carolina | 12 | 375 | 226 | 60.3 | 3001 | 8.0 | 27 | 10 | 145.93 | 31.3 | 250.1 |
| 12 | Syracuse | 11 | 316 | 209 | 66.1 | 2323 | 7.4 | 21 | 4 | 147.29 | 28.7 | 211.2 |
| 13 | Duke | 11 | 384 | 229 | 59.6 | 3685 | 9.6 | 32 | 8 | 163.58 | 34.9 | 335.0 |
| 14 | Georgia Tech | 11 | 315 | 211 | 67.0 | 3165 | 10.0 | 27 | 1 | 179.03 | 28.6 | 287.7 |