2021 American Athletic Conference Leaders Passing - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Desmond Ridder | Cincinnati | SR | QB | 7 | 163 | 112 | 68.7 | 1675 | 10.3 | 18 | 2 | 189.02 | 23.3 | 239.3 |
| 2 | Seth Henigan | Memphis | FR | QB | 7 | 218 | 134 | 61.5 | 1929 | 8.8 | 14 | 4 | 153.32 | 31.1 | 275.6 |
| 2 | Davis Brin | Tulsa | JR | QB | 6 | 166 | 94 | 56.6 | 1459 | 8.8 | 9 | 7 | 139.92 | 27.7 | 243.2 |
| 4 | Clayton Tune | Houston | JR | QB | 5 | 136 | 92 | 67.6 | 1164 | 8.6 | 8 | 3 | 154.55 | 27.2 | 232.8 |
| 5 | Tanner Mordecai | SMU | JR | QB | 6 | 247 | 167 | 67.6 | 2031 | 8.2 | 22 | 6 | 161.21 | 41.2 | 338.5 |
| 6 | Michael Pratt | Tulane | FR | QB | 6 | 146 | 87 | 59.6 | 1123 | 7.7 | 11 | 3 | 144.95 | 24.3 | 187.2 |
| 7 | Holton Ahlers | ECU | JR | QB | 6 | 179 | 105 | 58.7 | 1248 | 7.0 | 8 | 6 | 125.27 | 29.8 | 208.0 |
| 8 | Timmy McClain | S Florida | FR | QB | 6 | 147 | 74 | 50.3 | 999 | 6.8 | 5 | 4 | 113.21 | 24.5 | 166.5 |
| 9 | Mikey Keene | UCF | FR | QB | 6 | 141 | 94 | 66.7 | 864 | 6.1 | 7 | 2 | 131.69 | 23.5 | 144.0 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 15.0 pass attempts per game played.