2021 American Athletic Conference Leaders Passing - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tanner Mordecai | SMU | JR | QB | 1 | 28 | 17 | 60.7 | 245 | 8.8 | 4 | 3 | 159.92 | 28.0 | 245.0 |
| 2 | Davis Brin | Tulsa | JR | QB | 2 | 81 | 50 | 61.7 | 652 | 8.0 | 2 | 2 | 132.55 | 40.5 | 326.0 |
| 3 | Michael Pratt | Tulane | FR | QB | 2 | 62 | 37 | 59.7 | 462 | 7.5 | 5 | 0 | 148.89 | 31.0 | 231.0 |
| 4 | Clayton Tune | Houston | JR | QB | 2 | 78 | 53 | 67.9 | 457 | 5.9 | 4 | 5 | 121.27 | 39.0 | 228.5 |
| 5 | Seth Henigan | Memphis | FR | QB | 1 | 28 | 16 | 57.1 | 159 | 5.7 | 2 | 1 | 121.27 | 28.0 | 159.0 |
| 6 | Desmond Ridder | Cincinnati | SR | QB | 2 | 68 | 37 | 54.4 | 354 | 5.2 | 1 | 1 | 100.05 | 34.0 | 177.0 |
| 7 | Cade Fortin | S Florida | SO | QB | 2 | 38 | 19 | 50.0 | 132 | 3.5 | 0 | 2 | 68.65 | 19.0 | 66.0 |
| 8 | Holton Ahlers | ECU | JR | QB | 1 | 24 | 11 | 45.8 | 77 | 3.2 | 0 | 2 | 56.11 | 24.0 | 77.0 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 15.0 pass attempts per game played.