2021 American Athletic Conference Leaders Passing - Games in August/September Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tanner Mordecai | SMU | JR | QB | 4 | 139 | 98 | 70.5 | 1268 | 9.1 | 20 | 5 | 187.41 | 34.8 | 317.0 |
| 2 | Michael Pratt | Tulane | FR | QB | 4 | 124 | 72 | 58.1 | 882 | 7.1 | 10 | 2 | 141.20 | 31.0 | 220.5 |
| 3 | Seth Henigan | Memphis | FR | QB | 4 | 118 | 72 | 61.0 | 1170 | 9.9 | 9 | 1 | 167.79 | 29.5 | 292.5 |
| 3 | Dillon Gabriel | UCF | JR | QB | 3 | 102 | 70 | 68.6 | 814 | 8.0 | 9 | 3 | 158.90 | 34.0 | 271.3 |
| 5 | Desmond Ridder | Cincinnati | SR | QB | 3 | 83 | 54 | 65.1 | 748 | 9.0 | 7 | 2 | 163.77 | 27.7 | 249.3 |
| 6 | Davis Brin | Tulsa | JR | QB | 4 | 134 | 82 | 61.2 | 1209 | 9.0 | 5 | 5 | 141.82 | 33.5 | 302.3 |
| 6 | Holton Ahlers | ECU | JR | QB | 4 | 138 | 80 | 58.0 | 978 | 7.1 | 5 | 5 | 122.21 | 34.5 | 244.5 |
| 6 | Clayton Tune | Houston | JR | QB | 4 | 105 | 75 | 71.4 | 729 | 6.9 | 5 | 5 | 135.94 | 26.3 | 182.3 |
| 9 | D'Wan Mathis | Temple | FR | QB | 2 | 56 | 30 | 53.6 | 440 | 7.9 | 2 | 1 | 127.78 | 28.0 | 220.0 |
| 9 | Ike Ogbogu | Houston | JR | QB | 2 | 25 | 15 | 60.0 | 209 | 8.4 | 2 | 0 | 156.62 | 12.5 | 104.5 |
| 9 | Justin Lynch | Temple | FR | QB | 4 | 51 | 36 | 70.6 | 416 | 8.2 | 2 | 1 | 148.13 | 12.8 | 104.0 |
| 9 | Justin Ibieta | Tulane | FR | QB | 3 | 22 | 13 | 59.1 | 166 | 7.5 | 2 | 2 | 134.29 | 7.3 | 55.3 |
| 9 | Tyler Snead | ECU | SO | WR | 4 | 3 | 2 | 66.7 | 102 | 34.0 | 2 | 0 | 572.27 | 0.8 | 25.5 |
| 14 | Timmy McClain | S Florida | FR | QB | 4 | 70 | 40 | 57.1 | 558 | 8.0 | 1 | 2 | 123.11 | 17.5 | 139.5 |
| 14 | Mikey Keene | UCF | FR | QB | 1 | 7 | 4 | 57.1 | 55 | 7.9 | 1 | 0 | 170.28 | 7.0 | 55.0 |
| 14 | Evan Prater | Cincinnati | FR | QB | 2 | 4 | 1 | 25.0 | 18 | 4.5 | 1 | 1 | 95.30 | 2.0 | 9.0 |
| 14 | Ryan O'Keefe | UCF | JR | WR | 3 | 1 | 1 | 100.0 | 20 | 20.0 | 1 | 0 | 598.00 | 0.3 | 6.7 |