2021 American Athletic Conference Leaders Total Offense - Games in August/September Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tanner Mordecai | SMU | JR | QB | 4 | 121 | 1268 | 159 | 1389 | 8.74 | 347.3 |
| 2 | Davis Brin | Tulsa | JR | QB | 4 | 11 | 1209 | 154 | 1220 | 7.92 | 305.0 |
| 3 | Seth Henigan | Memphis | FR | QB | 4 | -15 | 1170 | 138 | 1155 | 8.37 | 288.8 |
| 4 | Holton Ahlers | ECU | JR | QB | 4 | 10 | 978 | 181 | 988 | 5.46 | 247.0 |
| 5 | Michael Pratt | Tulane | FR | QB | 4 | 96 | 882 | 162 | 978 | 6.04 | 244.5 |
| 6 | Dillon Gabriel | UCF | JR | QB | 3 | 125 | 814 | 126 | 939 | 7.45 | 313.0 |
| 7 | Desmond Ridder | Cincinnati | SR | QB | 3 | 72 | 748 | 103 | 820 | 7.96 | 273.3 |
| 8 | Clayton Tune | Houston | JR | QB | 4 | 68 | 729 | 132 | 797 | 6.04 | 199.3 |
| 9 | Timmy McClain | S Florida | FR | QB | 4 | 133 | 558 | 111 | 691 | 6.23 | 172.8 |
| 10 | D'Wan Mathis | Temple | FR | QB | 2 | 1 | 440 | 68 | 441 | 6.49 | 220.5 |
| 11 | Justin Lynch | Temple | FR | QB | 4 | 100 | 416 | 84 | 516 | 6.14 | 129.0 |
| 12 | Ike Ogbogu | Houston | JR | QB | 2 | -7 | 209 | 32 | 202 | 6.31 | 101.0 |
| 13 | Justin Ibieta | Tulane | FR | QB | 3 | 57 | 166 | 26 | 223 | 8.58 | 74.3 |
| 14 | Cade Fortin | S Florida | SO | QB | 2 | 17 | 132 | 45 | 149 | 3.31 | 74.5 |
| 15 | Xavier Arline | Navy | SO | QB | 3 | 171 | 109 | 65 | 280 | 4.31 | 93.3 |
| 16 | Tyler Snead | ECU | SO | WR | 4 | 4 | 102 | 6 | 106 | 17.67 | 26.5 |
| 17 | Maasai Maynor | Navy | JR | QB | 3 | -7 | 74 | 21 | 67 | 3.19 | 22.3 |
| 18 | Mikey Keene | UCF | FR | QB | 1 | 0 | 55 | 7 | 55 | 7.86 | 55.0 |
| 19 | Ryan O'Keefe | UCF | JR | WR | 3 | 18 | 20 | 2 | 38 | 19.00 | 12.7 |
| 20 | Evan Prater | Cincinnati | FR | QB | 2 | 52 | 18 | 11 | 70 | 6.36 | 35.0 |
| 21 | Quadry Jones | UCF | JR | WR | 1 | 5 | 14 | 2 | 19 | 9.50 | 19.0 |
| 21 | Katravis Marsh | S Florida | SO | QB | 2 | -4 | 14 | 5 | 10 | 2.00 | 5.0 |
| 23 | Kai Horton | Tulane | FR | QB | 2 | 5 | 9 | 3 | 14 | 4.67 | 7.0 |
| 24 | Tai Lavatai | Navy | SO | QB | 1 | 18 | 8 | 22 | 26 | 1.18 | 26.0 |
| 25 | Derek Green | SMU | JR | QB | 4 | 4 | 2 | 7 | 6 | 0.86 | 1.5 |