2021 American Athletic Conference Leaders Passing Defense - From Opponent's 40 to Own 40 Yard Line through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 12 | 87 | 52 | 59.8 | 543 | 1 | 6 | 102.19 | 53 | 27 | 10 | 3 |
| 1 | Cincinnati | 14 | 106 | 57 | 53.8 | 714 | 1 | 3 | 107.80 | 44 | 36 | 17 | 6 |
| 1 | UCF | 13 | 133 | 84 | 63.2 | 945 | 1 | 3 | 120.81 | 49 | 48 | 20 | 9 |
| 4 | Temple | 12 | 73 | 49 | 67.1 | 655 | 2 | 1 | 148.79 | 46 | 31 | 15 | 8 |
| 4 | Navy | 11 | 90 | 60 | 66.7 | 763 | 2 | 0 | 145.22 | 47 | 33 | 16 | 8 |
| 4 | Tulsa | 13 | 114 | 67 | 58.8 | 959 | 2 | 4 | 128.20 | 49 | 45 | 25 | 11 |
| 7 | Memphis | 12 | 104 | 67 | 64.4 | 949 | 3 | 3 | 144.82 | 53 | 44 | 21 | 10 |
| 8 | Houston | 14 | 111 | 66 | 59.5 | 809 | 4 | 4 | 125.36 | 50 | 34 | 19 | 11 |
| 8 | Tulane | 12 | 99 | 74 | 74.7 | 959 | 4 | 2 | 165.41 | 53 | 39 | 20 | 10 |
| 8 | South Florida | 12 | 107 | 73 | 68.2 | 980 | 4 | 6 | 146.29 | 55 | 45 | 20 | 11 |
| 8 | SMU | 12 | 98 | 59 | 60.2 | 1149 | 4 | 2 | 168.07 | 53 | 38 | 27 | 18 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||