2021 American Athletic Conference Leaders Opponent Penalties - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 4 | 32 | 286 | 8.0 | 71.5 |
| 2 | Tulane | 4 | 26 | 241 | 6.5 | 60.3 |
| 3 | SMU | 4 | 35 | 240 | 8.8 | 60.0 |
| 4 | Tulsa | 5 | 33 | 299 | 6.6 | 59.8 |
| 5 | Cincinnati | 5 | 42 | 296 | 8.4 | 59.2 |
| 6 | East Carolina | 4 | 25 | 211 | 6.3 | 52.8 |
| 7 | UCF | 5 | 29 | 245 | 5.8 | 49.0 |
| 8 | Navy | 4 | 19 | 170 | 4.8 | 42.5 |
| 9 | South Florida | 4 | 20 | 169 | 5.0 | 42.3 |
| 10 | Houston | 5 | 24 | 207 | 4.8 | 41.4 |
| 11 | Temple | 4 | 13 | 138 | 3.3 | 34.5 |