2021 American Athletic Conference Leaders Opponent Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Tulsa | 2 | 15 | 151 | 7.5 | 75.5 |
| 2 | UCF | 2 | 12 | 131 | 6.0 | 65.5 |
| 3 | SMU | 1 | 9 | 61 | 9.0 | 61.0 |
| 4 | Memphis | 1 | 8 | 59 | 8.0 | 59.0 |
| 5 | Tulane | 2 | 16 | 115 | 8.0 | 57.5 |
| 6 | East Carolina | 1 | 7 | 55 | 7.0 | 55.0 |
| 7 | Houston | 2 | 9 | 82 | 4.5 | 41.0 |
| 8 | Cincinnati | 2 | 11 | 81 | 5.5 | 40.5 |
| 9 | South Florida | 2 | 7 | 70 | 3.5 | 35.0 |
| 10 | Temple | 2 | 4 | 45 | 2.0 | 22.5 |