2021 American Athletic Conference Leaders Opponent Penalties - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Tulsa | 10 | 72 | 618 | 7.2 | 61.8 |
| 2 | Memphis | 10 | 61 | 588 | 6.1 | 58.8 |
| 3 | SMU | 10 | 73 | 555 | 7.3 | 55.5 |
| 4 | East Carolina | 10 | 56 | 504 | 5.6 | 50.4 |
| 5 | Cincinnati | 11 | 69 | 543 | 6.3 | 49.4 |
| 6 | Tulane | 9 | 43 | 427 | 4.8 | 47.4 |
| 7 | South Florida | 9 | 46 | 419 | 5.1 | 46.6 |
| 8 | UCF | 10 | 62 | 462 | 6.2 | 46.2 |
| 9 | Navy | 12 | 66 | 537 | 5.5 | 44.8 |
| 10 | Houston | 11 | 61 | 491 | 5.5 | 44.6 |
| 11 | Temple | 9 | 36 | 331 | 4.0 | 36.8 |