2021 American Athletic Conference Leaders Rushing Offense - Games in October Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 5 | 321 | 1217 | 3.79 | 9 | 64.20 | 243.40 |
| 2 | South Florida | 4 | 171 | 846 | 4.95 | 8 | 42.75 | 211.50 |
| 3 | East Carolina | 4 | 169 | 784 | 4.64 | 7 | 42.25 | 196.00 |
| 4 | Cincinnati | 5 | 163 | 927 | 5.69 | 13 | 32.60 | 185.40 |
| 5 | UCF | 5 | 181 | 882 | 4.87 | 9 | 36.20 | 176.40 |
| 6 | Tulsa | 4 | 153 | 664 | 4.34 | 5 | 38.25 | 166.00 |
| 7 | Tulane | 4 | 153 | 599 | 3.92 | 6 | 38.25 | 149.75 |
| 8 | Memphis | 4 | 145 | 585 | 4.03 | 7 | 36.25 | 146.25 |
| 9 | SMU | 4 | 131 | 466 | 3.56 | 7 | 32.75 | 116.50 |
| 10 | Houston | 4 | 143 | 455 | 3.18 | 6 | 35.75 | 113.75 |
| 11 | Temple | 4 | 109 | 419 | 3.84 | 2 | 27.25 | 104.75 |