2021 American Athletic Conference Leaders Tackles For Loss - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Houston | 13 | 89.0 | 372 | 6.85 |
| 2 | Cincinnati | 13 | 93.0 | 362 | 7.15 |
| 3 | UCF | 12 | 84.0 | 356 | 7.00 |
| 4 | Tulane | 11 | 78.0 | 305 | 7.09 |
| 5 | Memphis | 11 | 64.0 | 272 | 5.82 |
| 6 | Temple | 11 | 70.0 | 246 | 6.36 |
| 7 | East Carolina | 11 | 60.0 | 231 | 5.46 |
| 8 | SMU | 11 | 58.0 | 225 | 5.27 |
| 9 | Navy | 12 | 62.0 | 214 | 5.17 |
| 10 | Tulsa | 12 | 64.0 | 209 | 5.33 |
| 11 | South Florida | 11 | 45.0 | 145 | 4.09 |