2021 Big Ten Conference Leaders Long All Purpose Plays - Games at Home Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jayden Reed | Mich St | JR | WR | 6 | 12 | 7 | 4 | 4 | 3 | 2 | 0 |
| 1 | Samori Toure | Nebraska | SR | WR | 7 | 9 | 5 | 5 | 4 | 2 | 0 | 0 |
| 3 | Blake Corum | Michigan | SO | RB | 7 | 5 | 4 | 4 | 2 | 1 | 0 | 0 |
| 3 | Aron Cruickshank | Rutgers | JR | WR | 5 | 5 | 4 | 3 | 2 | 1 | 0 | 0 |
| 3 | Dontay Demus Jr. | Maryland | SR | WR | 4 | 5 | 3 | 2 | 2 | 0 | 0 | 0 |
| 3 | Emeka Egbuka | Ohio State | FR | WR | 6 | 6 | 3 | 2 | 2 | 1 | 1 | 0 |
| 3 | Charlie Jones | Iowa | SR | WR | 7 | 7 | 3 | 2 | 2 | 2 | 1 | 1 |
| 8 | Braelon Allen | Wisconsin | FR | RB | 7 | 5 | 2 | 2 | 1 | 1 | 0 | 0 |
| 8 | Daylen Baldwin | Michigan | SR | WR | 7 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | AJ Barner | Indiana | SO | TE | 6 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Ronnie Bell | Michigan | SR | WR | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Zavier Betts | Nebraska | FR | WR | 7 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 8 | Stephan Bracey | Wisconsin | SO | WR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 8 | Chase Brown | Illinois | SO | RB | 6 | 4 | 1 | 1 | 1 | 1 | 1 | 0 |
| 8 | Isaac Guerendo | Wisconsin | JR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 8 | Hassan Haskins | Michigan | SR | RB | 7 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | TreVeyon Henderson | Ohio State | FR | RB | 7 | 8 | 5 | 4 | 1 | 0 | 0 | 0 |
| 8 | A.J. Henning | Michigan | SO | WR | 7 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Jacolby Hewitt | Indiana | JR | WR | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Evan Hull | N'western | SO | RB | 6 | 6 | 2 | 1 | 1 | 1 | 1 | 1 |
| 8 | Rakim Jarrett | Maryland | SO | WR | 7 | 4 | 2 | 1 | 1 | 0 | 0 | 0 |
| 8 | Cornelius Johnson | Michigan | JR | WR | 7 | 4 | 2 | 2 | 1 | 1 | 1 | 0 |
| 8 | Brandon Joseph | N'western | SO | SAF | 6 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 8 | Ivory Kelly-Martin | Iowa | SR | RB | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Chester Kimbrough | Mich St | JR | CB | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | KeAndre Lambert-Smith | Penn State | SO | WR | 7 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 8 | Adrian Martinez | Nebraska | JR | QB | 6 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Cameron Martinez | Ohio State | FR | SAF | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | D.J. Matthews Jr. | Indiana | SR | WR | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 8 | Malick Meiga | Penn State | FR | WR | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Chez Mellusi | Wisconsin | JR | RB | 5 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Brandon Sanders | Rutgers | SR | WR | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Malik Washington | N'western | JR | WR | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Parker Washington | Penn State | SO | WR | 7 | 3 | 3 | 2 | 1 | 0 | 0 | 0 |
| 8 | Garrett Wilson | Ohio State | JR | WR | 7 | 4 | 3 | 3 | 1 | 1 | 0 | 0 |
| 8 | Jaquez Yant | Nebraska | FR | RB | 6 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Craig Young | Ohio State | SO | SAF | 7 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |