2021 Big Ten Conference Leaders Opponent First Downs - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Minnesota | 9 | 65 | 73 | 11 | 149 | 16.6 |
| 2 | Wisconsin | 9 | 34 | 74 | 15 | 123 | 13.7 |
| 3 | Purdue | 9 | 77 | 77 | 12 | 166 | 18.4 |
| 4 | Illinois | 9 | 93 | 78 | 7 | 178 | 19.8 |
| 5 | Penn State | 9 | 84 | 84 | 21 | 189 | 21.0 |
| 6 | Rutgers | 9 | 82 | 86 | 16 | 184 | 20.4 |
| 7 | Northwestern | 9 | 100 | 90 | 12 | 202 | 22.4 |
| 8 | Michigan | 10 | 67 | 94 | 10 | 171 | 17.1 |
| 9 | Nebraska | 9 | 70 | 95 | 13 | 178 | 19.8 |
| 10 | Iowa | 10 | 67 | 96 | 13 | 176 | 17.6 |
| 10 | Maryland | 9 | 90 | 96 | 21 | 207 | 23.0 |
| 12 | Indiana | 9 | 77 | 100 | 15 | 192 | 21.3 |
| 13 | Ohio State | 9 | 65 | 102 | 16 | 183 | 20.3 |
| 14 | Michigan State | 9 | 72 | 134 | 17 | 223 | 24.8 |