2021 Big Ten Conference Leaders Opponent First Downs - Games Won Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Northwestern | 3 | 15 | 24 | 3 | 42 | 14.0 |
| 1 | Indiana | 2 | 13 | 24 | 0 | 37 | 18.5 |
| 3 | Nebraska | 3 | 17 | 28 | 3 | 48 | 16.0 |
| 4 | Rutgers | 5 | 30 | 30 | 8 | 68 | 13.6 |
| 5 | Illinois | 5 | 35 | 40 | 8 | 83 | 16.6 |
| 6 | Maryland | 7 | 49 | 54 | 15 | 118 | 16.9 |
| 7 | Wisconsin | 9 | 38 | 59 | 13 | 110 | 12.2 |
| 8 | Penn State | 7 | 51 | 73 | 17 | 141 | 20.1 |
| 9 | Minnesota | 9 | 57 | 75 | 12 | 144 | 16.0 |
| 10 | Purdue | 9 | 77 | 78 | 12 | 167 | 18.6 |
| 11 | Iowa | 10 | 65 | 89 | 11 | 165 | 16.5 |
| 12 | Michigan | 12 | 77 | 107 | 14 | 198 | 16.5 |
| 13 | Ohio State | 11 | 69 | 133 | 24 | 226 | 20.5 |
| 14 | Michigan State | 11 | 87 | 144 | 20 | 251 | 22.8 |