2021 Big Ten Conference Leaders Interceptions - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Ohio State | 13 | 12 | 306 | 4 | 0.92 |
| 2 | Wisconsin | 13 | 16 | 235 | 2 | 1.23 |
| 3 | Michigan State | 12 | 9 | 232 | 2 | 0.75 |
| 4 | Iowa | 14 | 25 | 225 | 3 | 1.79 |
| 5 | Penn State | 12 | 13 | 171 | 3 | 1.08 |
| 6 | Purdue | 13 | 13 | 107 | 1 | 1.00 |
| 7 | Michigan | 14 | 8 | 101 | 1 | 0.57 |
| 8 | Minnesota | 13 | 8 | 99 | 0 | 0.62 |
| 9 | Rutgers | 12 | 7 | 88 | 1 | 0.58 |
| 10 | Nebraska | 11 | 7 | 56 | 0 | 0.64 |
| 11 | Maryland | 12 | 5 | 54 | 0 | 0.42 |
| 12 | Indiana | 11 | 5 | 42 | 0 | 0.45 |
| 13 | Illinois | 12 | 9 | 39 | 0 | 0.75 |
| 14 | Northwestern | 11 | 6 | 29 | 0 | 0.55 |