2021 Big Ten Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Michigan State | 11 | 9 | 232 | 2 | 0.82 |
| 2 | Wisconsin | 10 | 15 | 229 | 2 | 1.50 |
| 3 | Iowa | 12 | 25 | 225 | 3 | 2.08 |
| 4 | Penn State | 11 | 11 | 156 | 2 | 1.00 |
| 4 | Ohio State | 11 | 8 | 156 | 2 | 0.73 |
| 6 | Purdue | 11 | 12 | 107 | 1 | 1.09 |
| 7 | Michigan | 12 | 7 | 74 | 1 | 0.58 |
| 8 | Minnesota | 11 | 6 | 71 | 0 | 0.55 |
| 9 | Maryland | 11 | 5 | 54 | 0 | 0.45 |
| 10 | Indiana | 9 | 4 | 42 | 0 | 0.44 |
| 11 | Illinois | 10 | 8 | 37 | 0 | 0.80 |
| 12 | Nebraska | 10 | 6 | 34 | 0 | 0.60 |
| 13 | Rutgers | 11 | 5 | 21 | 0 | 0.45 |
| 14 | Northwestern | 10 | 4 | 3 | 0 | 0.40 |