2021 Pac-12 Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Washington | 3 | 525 | 369 | 200 | 894 | 4.47 | 298.0 |
| 2 | Colorado | 3 | 394 | 591 | 199 | 985 | 4.95 | 328.3 |
| 3 | Arizona | 3 | 547 | 482 | 197 | 1029 | 5.22 | 343.0 |
| 4 | Arizona State | 4 | 467 | 567 | 233 | 1034 | 4.44 | 258.5 |
| 5 | USC | 3 | 404 | 797 | 210 | 1201 | 5.72 | 400.3 |
| 6 | UCLA | 3 | 188 | 1028 | 236 | 1216 | 5.15 | 405.3 |
| 7 | Stanford | 3 | 616 | 636 | 200 | 1252 | 6.26 | 417.3 |
| 8 | California | 3 | 391 | 954 | 223 | 1345 | 6.03 | 448.3 |
| 9 | Oregon State | 4 | 391 | 1036 | 288 | 1427 | 4.95 | 356.8 |
| 10 | Utah | 4 | 602 | 979 | 270 | 1581 | 5.86 | 395.3 |
| 11 | Washington State | 4 | 709 | 893 | 301 | 1602 | 5.32 | 400.5 |
| 12 | Oregon | 4 | 667 | 1155 | 290 | 1822 | 6.28 | 455.5 |