2021 Louisville Cardinals Opponent Penalty Game Log through 01/10/2022
| Date | Opponent | Surface | Result | Pen. | Yards | Pen./G | Yards/G |
|---|---|---|---|---|---|---|---|
| 09/06/21 | + 11 Mississippi | Turf | L 24-43 | 14 | 125 | 14.0 | 125.0 |
| 09/11/21 | Eastern Ky. | Turf | W 30-3 | 2 | 15 | 2.0 | 15.0 |
| 09/17/21 | UCF | Turf | W 42-35 | 7 | 55 | 7.0 | 55.0 |
| 09/25/21 | @ Florida St. | Grass | W 31-23 | 4 | 30 | 4.0 | 30.0 |
| 10/02/21 | @ 15 Wake Forest | Turf | L 34-37 | 6 | 35 | 6.0 | 35.0 |
| 10/09/21 | Virginia | Turf | L 33-34 | 7 | 56 | 7.0 | 56.0 |
| 10/23/21 | Boston College | Turf | W 28-14 | 5 | 45 | 5.0 | 45.0 |
| 10/30/21 | @ 20 North Carolina St. | Grass | L 13-28 | 5 | 45 | 5.0 | 45.0 |
| 11/06/21 | 14 Clemson | Turf | L 24-30 | 3 | 30 | 3.0 | 30.0 |
| 11/13/21 | Syracuse | Turf | W 41-3 | 8 | 52 | 8.0 | 52.0 |
| 11/18/21 | @ Duke | Grass | W 62-22 | 4 | 35 | 4.0 | 35.0 |
| 11/27/21 | 18 Kentucky | Turf | L 21-52 | 4 | 29 | 4.0 | 29.0 |
| 12/28/21 | + Air Force | Turf | L 28-31 | 3 | 35 | 3.0 | 35.0 |
| Totals | 72 | 587 | 5.5 | 45.2 | |||
| @ : Away, + : Neutral Site | |||||||