2022 Conference USA Leaders Total Defense - Games in November Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 3 | 259 | 772 | 163 | 1031 | 6.33 | 343.7 |
| 2 | UTSA | 4 | 591 | 949 | 281 | 1540 | 5.48 | 385.0 |
| 3 | Western Kentucky | 4 | 756 | 789 | 289 | 1545 | 5.35 | 386.3 |
| 4 | North Texas | 3 | 570 | 601 | 204 | 1171 | 5.74 | 390.3 |
| 5 | Rice | 4 | 693 | 871 | 234 | 1564 | 6.68 | 391.0 |
| 6 | Charlotte | 3 | 371 | 877 | 188 | 1248 | 6.64 | 416.0 |
| 7 | Middle Tennessee | 4 | 355 | 1327 | 292 | 1682 | 5.76 | 420.5 |
| 8 | UAB | 4 | 803 | 990 | 283 | 1793 | 6.34 | 448.3 |
| 9 | Louisiana Tech | 4 | 1004 | 811 | 278 | 1815 | 6.53 | 453.8 |
| 10 | Florida Atlantic | 3 | 531 | 932 | 239 | 1463 | 6.12 | 487.7 |
| 11 | Florida International | 4 | 993 | 987 | 323 | 1980 | 6.13 | 495.0 |