2020 Conference USA Leaders Total Defense - Games in November Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Marshall | 2 | 97 | 396 | 123 | 493 | 4.01 | 246.5 |
| 2 | Florida Atlantic | 3 | 312 | 435 | 188 | 747 | 3.97 | 249.0 |
| 3 | Western Kentucky | 3 | 440 | 322 | 194 | 762 | 3.93 | 254.0 |
| 4 | Southern Mississippi | 3 | 377 | 406 | 188 | 783 | 4.16 | 261.0 |
| 5 | UTSA | 3 | 336 | 658 | 187 | 994 | 5.32 | 331.3 |
| 6 | Florida International | 2 | 538 | 201 | 127 | 739 | 5.82 | 369.5 |
| 7 | Rice | 1 | 269 | 120 | 62 | 389 | 6.27 | 389.0 |
| 8 | Middle Tennessee | 2 | 276 | 636 | 137 | 912 | 6.66 | 456.0 |
| 9 | North Texas | 2 | 492 | 508 | 140 | 1000 | 7.14 | 500.0 |
| 10 | UTEP | 1 | 288 | 312 | 76 | 600 | 7.89 | 600.0 |