2022 Conference USA Leaders Passes Defended - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 7 | 11 | 51 | 62 | 8.86 |
| 2 | UTSA | 7 | 10 | 37 | 47 | 6.71 |
| 3 | UAB | 7 | 6 | 37 | 43 | 6.14 |
| 4 | Western Kentucky | 8 | 12 | 27 | 39 | 4.88 |
| 5 | Louisiana Tech | 6 | 5 | 26 | 31 | 5.17 |
| 6 | North Texas | 6 | 5 | 25 | 30 | 5.00 |
| 7 | Florida Atlantic | 5 | 8 | 20 | 28 | 5.60 |
| 8 | Rice | 6 | 2 | 24 | 26 | 4.33 |
| 9 | UTEP | 8 | 4 | 19 | 23 | 2.88 |
| 10 | Florida International | 7 | 6 | 16 | 22 | 3.14 |
| 11 | Charlotte | 6 | 5 | 16 | 21 | 3.50 |