2022 Atlantic Coast Conference Leaders Passes Defended - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 9 | 7 | 43 | 50 | 5.56 |
| 2 | Pittsburgh | 8 | 6 | 40 | 46 | 5.75 |
| 3 | North Carolina | 9 | 6 | 37 | 43 | 4.78 |
| 4 | Wake Forest | 8 | 2 | 36 | 38 | 4.75 |
| 5 | Duke | 8 | 8 | 30 | 38 | 4.75 |
| 6 | Miami (Florida) | 8 | 9 | 29 | 38 | 4.75 |
| 6 | Virginia Tech | 7 | 4 | 29 | 33 | 4.71 |
| 8 | North Carolina State | 8 | 10 | 28 | 38 | 4.75 |
| 8 | Georgia Tech | 8 | 6 | 28 | 34 | 4.25 |
| 10 | Virginia | 7 | 4 | 26 | 30 | 4.29 |
| 10 | Boston College | 8 | 4 | 26 | 30 | 3.75 |
| 12 | Louisville | 8 | 12 | 23 | 35 | 4.38 |
| 13 | Florida State | 8 | 7 | 22 | 29 | 3.63 |
| 14 | Syracuse | 8 | 7 | 19 | 26 | 3.25 |