2022 Atlantic Coast Conference Leaders Passes Defended - Games in October Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 4 | 2 | 22 | 24 | 6.00 |
| 2 | Georgia Tech | 4 | 4 | 21 | 25 | 6.25 |
| 3 | Boston College | 4 | 3 | 19 | 22 | 5.50 |
| 3 | Wake Forest | 4 | 1 | 19 | 20 | 5.00 |
| 5 | North Carolina | 4 | 3 | 18 | 21 | 5.25 |
| 5 | Virginia | 4 | 3 | 18 | 21 | 5.25 |
| 5 | Pittsburgh | 4 | 2 | 18 | 20 | 5.00 |
| 8 | Miami (Florida) | 4 | 2 | 17 | 19 | 4.75 |
| 8 | Virginia Tech | 4 | 1 | 17 | 18 | 4.50 |
| 10 | Duke | 4 | 4 | 14 | 18 | 4.50 |
| 11 | Florida State | 4 | 1 | 12 | 13 | 3.25 |
| 12 | Louisville | 4 | 9 | 11 | 20 | 5.00 |
| 12 | North Carolina State | 4 | 4 | 11 | 15 | 3.75 |
| 14 | Syracuse | 4 | 4 | 9 | 13 | 3.25 |