2022 Atlantic Coast Conference Leaders Passes Defended - Games in December/January Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 2 | 2 | 8 | 10 | 5.00 |
| 2 | Wake Forest | 1 | 0 | 6 | 6 | 6.00 |
| 3 | North Carolina State | 1 | 2 | 4 | 6 | 6.00 |
| 3 | Duke | 1 | 1 | 4 | 5 | 5.00 |
| 3 | North Carolina | 2 | 1 | 4 | 5 | 2.50 |
| 3 | Louisville | 1 | 0 | 4 | 4 | 4.00 |
| 7 | Florida State | 1 | 0 | 3 | 3 | 3.00 |
| 8 | Pittsburgh | 1 | 4 | 2 | 6 | 6.00 |
| 9 | Syracuse | 1 | 0 | 1 | 1 | 1.00 |