2022 Atlantic Coast Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | North Carolina State | 5 | 9 | 20 | 29 | 5.80 |
| 2 | Pittsburgh | 5 | 8 | 27 | 35 | 7.00 |
| 3 | Clemson | 5 | 6 | 21 | 27 | 5.40 |
| 4 | Wake Forest | 5 | 5 | 27 | 32 | 6.40 |
| 4 | Miami (Florida) | 4 | 5 | 12 | 17 | 4.25 |
| 4 | Georgia Tech | 4 | 5 | 6 | 11 | 2.75 |
| 7 | Boston College | 4 | 3 | 15 | 18 | 4.50 |
| 7 | Louisville | 5 | 3 | 15 | 18 | 3.60 |
| 7 | North Carolina | 5 | 3 | 12 | 15 | 3.00 |
| 7 | Syracuse | 5 | 3 | 9 | 12 | 2.40 |
| 11 | Duke | 5 | 2 | 28 | 30 | 6.00 |
| 12 | Florida State | 5 | 1 | 23 | 24 | 4.80 |
| 12 | Virginia | 3 | 1 | 11 | 12 | 4.00 |
| 14 | Virginia Tech | 4 | 0 | 12 | 12 | 3.00 |