2022 Atlantic Coast Conference Leaders Passes Defended - Games in November Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Miami (Florida) | 4 | 7 | 12 | 19 | 4.75 |
| 2 | North Carolina State | 4 | 6 | 17 | 23 | 5.75 |
| 3 | Pittsburgh | 4 | 4 | 22 | 26 | 6.50 |
| 3 | Duke | 4 | 4 | 16 | 20 | 5.00 |
| 3 | Florida State | 4 | 4 | 16 | 20 | 5.00 |
| 3 | Clemson | 4 | 4 | 13 | 17 | 4.25 |
| 7 | North Carolina | 4 | 3 | 17 | 20 | 5.00 |
| 8 | Wake Forest | 4 | 2 | 16 | 18 | 4.50 |
| 8 | Virginia Tech | 3 | 2 | 12 | 14 | 4.67 |
| 8 | Georgia Tech | 4 | 2 | 7 | 9 | 2.25 |
| 8 | Syracuse | 4 | 2 | 6 | 8 | 2.00 |
| 12 | Louisville | 4 | 1 | 12 | 13 | 3.25 |
| 12 | Boston College | 4 | 1 | 10 | 11 | 2.75 |
| 14 | Virginia | 2 | 0 | 4 | 4 | 2.00 |