2022 Atlantic Coast Conference Leaders Interceptions - Games vs. FBS (I-A) Teams Only through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | North Carolina State | 12 | 17 | 170 | 1 | 1.42 |
| 2 | Louisville | 13 | 15 | 252 | 2 | 1.15 |
| 3 | Pittsburgh | 12 | 14 | 215 | 4 | 1.17 |
| 4 | Clemson | 13 | 12 | 153 | 2 | 0.92 |
| 5 | Miami (Florida) | 11 | 11 | 104 | 1 | 1.00 |
| 6 | Duke | 12 | 10 | 93 | 1 | 0.83 |
| 7 | Syracuse | 12 | 9 | 86 | 1 | 0.75 |
| 8 | Georgia Tech | 11 | 8 | 26 | 1 | 0.73 |
| 8 | Florida State | 12 | 8 | 10 | 0 | 0.67 |
| 8 | North Carolina | 13 | 8 | 93 | 0 | 0.62 |
| 11 | Wake Forest | 12 | 7 | 88 | 2 | 0.58 |
| 12 | Virginia | 9 | 5 | 40 | 0 | 0.56 |
| 12 | Boston College | 11 | 5 | 38 | 0 | 0.45 |
| 14 | Virginia Tech | 10 | 4 | 38 | 1 | 0.40 |