2022 Atlantic Coast Conference Leaders Interceptions - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | North Carolina State | 11 | 17 | 167 | 1 | 1.55 |
| 2 | Miami (Florida) | 9 | 11 | 132 | 2 | 1.22 |
| 2 | Louisville | 10 | 11 | 204 | 2 | 1.10 |
| 2 | Clemson | 10 | 11 | 118 | 1 | 1.10 |
| 5 | Georgia Tech | 8 | 10 | 55 | 1 | 1.25 |
| 5 | Pittsburgh | 11 | 10 | 202 | 4 | 0.91 |
| 7 | North Carolina | 10 | 8 | 67 | 0 | 0.80 |
| 7 | Florida State | 11 | 8 | 10 | 0 | 0.73 |
| 7 | Duke | 12 | 8 | 60 | 1 | 0.67 |
| 10 | Wake Forest | 11 | 7 | 88 | 2 | 0.64 |
| 11 | Boston College | 9 | 6 | 87 | 0 | 0.67 |
| 12 | Syracuse | 9 | 5 | 80 | 2 | 0.56 |
| 12 | Virginia | 9 | 5 | 40 | 0 | 0.56 |
| 14 | Virginia Tech | 10 | 3 | 38 | 1 | 0.30 |