2022 American Athletic Conference Leaders Passes Defended - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Cincinnati | 6 | 7 | 28 | 35 | 5.83 |
| 2 | Houston | 7 | 4 | 28 | 32 | 4.57 |
| 3 | Memphis | 6 | 11 | 15 | 26 | 4.33 |
| 4 | Navy | 3 | 5 | 16 | 21 | 7.00 |
| 5 | East Carolina | 4 | 2 | 17 | 19 | 4.75 |
| 6 | SMU | 4 | 4 | 11 | 15 | 3.75 |
| 6 | Tulsa | 4 | 2 | 13 | 15 | 3.75 |
| 6 | Temple | 5 | 5 | 10 | 15 | 3.00 |
| 6 | UCF | 5 | 1 | 14 | 15 | 3.00 |
| 10 | Tulane | 3 | 3 | 3 | 6 | 2.00 |
| 11 | South Florida | 3 | 2 | 2 | 4 | 1.33 |