2022 American Athletic Conference Leaders Passes Defended - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Cincinnati | 12 | 11 | 44 | 55 | 4.58 |
| 1 | Houston | 12 | 8 | 47 | 55 | 4.58 |
| 3 | Tulane | 12 | 11 | 43 | 54 | 4.50 |
| 4 | UCF | 12 | 5 | 46 | 51 | 4.25 |
| 5 | East Carolina | 12 | 11 | 39 | 50 | 4.17 |
| 6 | Memphis | 11 | 15 | 29 | 44 | 4.00 |
| 6 | Temple | 12 | 6 | 38 | 44 | 3.67 |
| 8 | Navy | 11 | 7 | 33 | 40 | 3.64 |
| 8 | Tulsa | 11 | 5 | 35 | 40 | 3.64 |
| 10 | SMU | 11 | 10 | 29 | 39 | 3.55 |
| 11 | South Florida | 11 | 6 | 19 | 25 | 2.27 |