2022 American Athletic Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Houston | 5 | 6 | 20 | 26 | 5.20 |
| 2 | Memphis | 5 | 8 | 14 | 22 | 4.40 |
| 3 | Cincinnati | 5 | 6 | 15 | 21 | 4.20 |
| 3 | UCF | 5 | 1 | 20 | 21 | 4.20 |
| 5 | East Carolina | 5 | 3 | 17 | 20 | 4.00 |
| 6 | SMU | 5 | 4 | 13 | 17 | 3.40 |
| 7 | Temple | 4 | 2 | 12 | 14 | 3.50 |
| 7 | Tulane | 5 | 5 | 9 | 14 | 2.80 |
| 9 | South Florida | 4 | 4 | 8 | 12 | 3.00 |
| 10 | Tulsa | 4 | 2 | 9 | 11 | 2.75 |
| 11 | Navy | 4 | 1 | 7 | 8 | 2.00 |