2018 American Athletic Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 10 | 1053 | 1962 | 643 | 3015 | 4.69 | 301.5 |
| 2 | Temple | 9 | 1726 | 1531 | 724 | 3257 | 4.50 | 361.9 |
| 3 | Tulane | 10 | 1434 | 2337 | 710 | 3771 | 5.31 | 377.1 |
| 4 | Memphis | 11 | 1871 | 2774 | 856 | 4645 | 5.43 | 422.3 |
| 5 | Tulsa | 9 | 2278 | 1562 | 666 | 3840 | 5.77 | 426.7 |
| 6 | Navy | 12 | 2328 | 2879 | 785 | 5207 | 6.63 | 433.9 |
| 7 | East Carolina | 9 | 1560 | 2399 | 647 | 3959 | 6.12 | 439.9 |
| 8 | SMU | 9 | 1867 | 2163 | 724 | 4030 | 5.57 | 447.8 |
| 9 | UCF | 10 | 2443 | 2111 | 815 | 4554 | 5.59 | 455.4 |
| 10 | South Florida | 10 | 2395 | 2195 | 779 | 4590 | 5.89 | 459.0 |
| 11 | Houston | 10 | 2568 | 2318 | 815 | 4886 | 6.00 | 488.6 |
| 12 | Connecticut | 10 | 3480 | 2743 | 701 | 6223 | 8.88 | 622.3 |